A Simple Method for Analysis of Titration Curves of Polyprotic Acids
Abstract
In the present work, the titration curves of polyrpotic acid were analyzed theoretically on the basis of general equilibrium constants expression for evaluation of formation and dissociation constants. The present work provides more insight into the analysis of titration curves and development of distribution diagrams. The formation-dissociation curves of oxalic acids were also analyzed for finding a general relation between formation and dissociation process. It was concluded that the present method of treatment of titration curves is applicable to analyze the complex acid-base equilibria.References
T. M. David, Perspect. Medicin. Chem. 1 (2007) 25.
R. I. Allen, K. J. Box, J.E.A. Comer, C. Peake and K. Y. Tam,
J. Pharm. Biomed. Anal. 17 (1998) 699.
B. B. Brodie, H. Kurz and L. S. Schanker, J. Pharmacol. Exper.
Therap. 130 (1960) 20.
A. G. Asuero, Crit. Rev. Anal. Chem. 37 (2007) 269.
M. V. D. Steene, L. V. Vooren, J. P. Ottoy and P. A. Vanrolleghem,
Environ. Sci. Technol. 36 (2002) 715.
P. J. Elving, J. M. Markowitz and I. Rosenthal, Anal. Chem. 28
(1956) 1179.
B. Donald and D. V. Slyke, in: On the measurement of buffer values
and on the relationship of buffer value to the dissociation constant of
the buffer and the concentration and reaction of the buffer solution
(1922).
A. S. A. Khan, Turk. J. Chem. 36 (2012) 219.
F. J. C. Rossotii and H. Rossotti, in: The determination of stability
constants and other equilibrium constants in solutions, McGraw-Hill,
Book Company, Inc, New York, USA (1961) pp.38.
A. Albert and E. P. Serjeant, in: The determination of Ionization
constants, 3rd Edition, Chapman and Hall, USA (1984) pp.59.
T. Michalowski, A. Pietrzyk, M. P. Svet and M. Rymanowski, Crit.
Rev. Anal. Chem. 40 (2010) 17.
